Health, Medicine

BRAF p.V600E-specific immunohistochemical assessment in colorectal cancer endoscopy biopsies is consistent with the mutational profiling

Abstract

The assessment of BRAF p.V600E mutational status has already become an essential part of the diagnostic routine in colorectal cancer (CRC). Indeed, on one side, the BRAF mutational status is regarded as being a key molecular marker to definitely decide the most proper therapeutic options in a selected cohort of patients. On the other, it is used to exclude a suspicious of Lynch Syndrome in case of MLH1 absence in deficient mismatch repair (dMMR) tumors [1].

This article is protected by copyright. All rights reserved.

from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/2u7e0wp

http://ift.tt/2uI7srx

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s