Health, Medicine

BRAF p.V600E-specific immunohistochemical assessment in colorectal cancer endoscopy biopsies is consistent with the mutational profiling


The assessment of BRAF p.V600E mutational status has already become an essential part of the diagnostic routine in colorectal cancer (CRC). Indeed, on one side, the BRAF mutational status is regarded as being a key molecular marker to definitely decide the most proper therapeutic options in a selected cohort of patients. On the other, it is used to exclude a suspicious of Lynch Syndrome in case of MLH1 absence in deficient mismatch repair (dMMR) tumors [1].

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from Anatomy Pathology via xlomafota13 on Inoreader


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